Bystolic 5 mg


Bystolic pills
Bystolic pills contain nebivolol hydrochloride equivalent to 2.5, 5, 10, and 20 mg
Generic Name: Nebivolol

What is Bystolic?

Bystolic is used to treat high blood pressure. Bystolic belongs to a group of drugs called beta-blockers.

Bystolic dosing

Bystolic as pills for oral administration contains nebivolol hydrochloride equivalent to 2.5, 5, 10, and 20 mg of nebivolol base.
The usual starting dose of Bystolic for most people with high blood pressure is 5 mg once daily. If your blood pressure levels do not improve, your healthcare provider may gradually increase your dose up to a maximum of 40 mg daily. People with severe kidney problems or moderate liver problems may need to start with lower Bystolic dosage, such as 2.5 mg once daily.

What are the possible side effects of Bystolic pills?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:
- feeling short of breath, even with mild exertion;
- swelling of your ankles or feet;
- slow or uneven heartbeats; or
- numbness or cold feeling in your hands and feet.

Less serious side effects may include:
- headache;
- tired feeling;
- nausea, stomach pain;
- diarrhea; or
- sleep problems (insomnia).

Important information about Bystolic pills

Do not skip doses or stop taking Bystolic without first talking to your doctor. Stopping suddenly may make your condition worse or cause other serious heart problems such as severe chest pain or heart attack. You may need to use less and less before you stop the medication completely. If you need surgery, tell the surgeon ahead of time that you are using Bystolic.
Bystolic is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Keep using Bystolic as directed, even if you feel well. High blood pressure often has no symptoms. You may need to treat high blood pressure for the rest of your life.

Before taking Bystolic

You should not take Bystolic if you are allergic to nebivolol, or if you have:
- severe liver disease; or
- a heart problem such as heart block, sick sinus syndrome, slow heart rate, or heart failure.

If you have any of these other conditions, you may need a Bystolic dose adjustment or special tests:
- asthma, bronchitis, emphysema;
- liver or kidney disease;
- diabetes;
- a thyroid disorder;
- a history of allergies;
- problems with circulation (such as Raynaud's syndrome);
- pheochromocytoma (tumor of the adrenal gland); or
- if you have recently had a heart attack.

Bystolic Side Effects

The data described below reflect worldwide clinical trial exposure to Bystolic in 6545 patients, including 5038 patients treated for hypertension and the remaining 1507 subjects treated for other cardiovascular diseases. Doses ranged from 0.5 mg to 40 mg. Patients received Bystolic for up to 24 months, with over 1900 patients treated for at least 6 months, and approximately 1300 patients for more than one year. In placebo-controlled clinical trials comparing Bystolic with placebo, discontinuation of therapy due to adverse events was reported in 2.8% of patients treated with nebivolol and 2.2% of patients given placebo. The most common adverse events that led to discontinuation of Bystolic were headache (0.4%), nausea (0.2%) and bradycardia (0.2%).

Table 2 lists treatment-emergent signs and symptoms that were reported in three 12-week, placebo-controlled monotherapy trials involving 1597 hypertensive patients treated with either 5 mg, 10 mg or 20-40 mg of Bystolic and 205 patients given placebo and for which the rate of occurrence was at least 1% of patients treated with nebivolol and greater than the rate for those treated with placebo in at least one dose group.


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